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Znosko Lab CoSSMos Database

Welcome to version 2.0 of the RNA CoSSmos database. This version has been under development and replaces the first version which was found at Feel free to explore and send feedback via the Contact link found in the upper right of every page.

We believe that all debugging lines have been removed from the new version of CoSSMos; if you see strange text that looks like it does not belong on a page, please send the url to the authors using the Contact link and we will take a look.

Welcome to the Znosko Lab RNA Characterization of Secondary Structure Motifs (RNA CoSSMos) database! This tool allows the systematic searching of all catalogued three-dimensional nucleic acid PDB structures that contain secondary structure motifs such as mismatches, (a)symmetric internal loops, hairpin loops, and bulge loops.

To utilize the search function of the database, please select "Search" at the top menu.

If you have any questions, please check out our Wiki here or e-mail us via the Contact Us page. Also, please consider registering with the CoSSMos database if this is your first visit.

This site functions best at resolutions of at least 1440x900. It has been developed using Chrome (v71 and beyond), which is the recommended browser for this site. We have done some testing with newer versions (2018 and beyond) of Internet Explorer, Firefox, and Safari.

Lastly, users of the RNA CoSSMos database should cite:

Vanegas, P. L., Hudson, G. A., Davis, A. R., Kelly, S. C., Kirkpatrick, C. C., and Znosko, B. M. (2012) RNA CoSSMos: Characterization of Secondary Structure Motifs- a searchable database of secondary structure motifs in RNA three-dimensional structures, Nucleic Acids Res. 40, D439-D444.

and are encouraged to cite:

Gendron, P., Lemieux, S., and Major, F. (2001) Quantitative analysis of nucleic acid three-dimensional structures., J. Mol. Biol. 308, 919-936.

Lemieux, S., and Major, F. (2002) RNA canonical and non-canonical base pairing types: a recognition method and complete repertoire., Nucleic Acids Res. 30, 4250-4263.

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